Genetic diagnosis is becoming increasingly sophisticated, with the ability to identify
even fine differences in patients with a wide variety of congenital heart lesions.
Although we have an incomplete understanding of the clinical consequences of most
genetic findings, some categories of mutations can have important implications for
disease recurrence and prognosis. Consideration of the biology underlying a genetic
deficiency, when known, can be useful in the clinical management of some patients.
Keywords
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Article info
Footnotes
This work was supported in part by the NIH/NHLBI Pediatric Cardiac Genomics Consortium (5 UM1HL098162-11).
Conflict of Interest: None.
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© 2021 Published by Elsevier Inc.
